Optimal mean arterial pressure and its objective statistical associations with clinical outcomes and multimodal monitoring cerebral physiology: A systematic scoping review.

ABSTRACT: Optimal mean arterial pressure (MAPopt), also known as optimal arterial blood pressure (ABPopt), represents a patient-specific blood pressure range at which cerebral autoregulation is most intact. To date, literature on this personalized physiological target remains heterogeneous, scattered, and difficult to follow. This scoping review, following PRISMA-ScR guidelines, examined studies that explored objective statistical associations between MAPopt and clinical outcomes and multimodal monitoring (MMM) cerebral physiology. Fifteen articles met the inclusion criteria for studies investigating the relationship between MAPopt and outcome, including seven neonatal studies, five cardiac arrest/surgery studies, two general ICU (Intensive Care Unit) studies, and one neurological ICU study. Fourtee

SUBMITTER: Hasan R 

PROVIDER: S-EPMC12451020 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature