Changes in quality of vitamin K antagonist treatment and clinical outcomes during Ramadan: a Dutch population-based cohort study.

ABSTRACT:

Background

Ramadan fasting alters the timing and content of food, including dietary vitamin K, and medication intake, potentially affecting stability of vitamin K antagonist (VKA) treatment and clinical outcomes.

Objectives

To assess population-level changes in VKA treatment quality and incidence of clinical events, including bleeding and venous and arterial thromboembolism, during Ramadan in the Netherlands.

Methods

Data from 17 Dutch anticoagulation clinics were linked to Statistics Netherlands. Prevalent VKA users in 2013-2019 with an immigration background who were likely to fast during Ramadan (ie, the Ramadan cohort) were studied from 2 months preceding Ramadan until 2 months after. During each 30-day interval, VKA treatment quality and risk of clinical events w

SUBMITTER: Kempers EK 

PROVIDER: S-EPMC12451347 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature