National trends in mortality associated with obstructive sleep apnea among adults with diabetes mellitus in the United States, 1999-2020.

ABSTRACT:

Background

Obstructive sleep apnea (OSA) and diabetes mellitus are two prevalent and interrelated chronic conditions that contribute significantly to cardiovascular and metabolic mortality. However, national trends in OSA-related mortality among adults with diabetes remain poorly characterized.

Methods

We conducted a cross-sectional analysis of U.S. death certificate data from 1999 to 2020 using the CDC WONDER platform. Adults aged ≥25 years with diabetes mellitus (ICD-10: E10-E14) as the underlying cause of death and OSA (G47.33) as a contributing cause were included. Age-adjusted mortality rates (AAMRs) were calculated per 100,000 population, and temporal trends were assessed using Joinpoint regression.

Results

A total of 79,728 deaths were attributed to diabetes an

SUBMITTER: Hassan IN 

PROVIDER: S-EPMC12451354 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature