Insight into the oxidase-mimicking activity enhancement of MnO₂ nanozymes by Co ion-doping for colorimetric sensor assays.

ABSTRACT: Manganese dioxide (MnO₂) nanomaterials have garnered significant attention as enzyme mimics due to their excellent catalytic properties. However, when applied to catalytic oxidation in biological systems, pure MnO₂ has shown limited performance. To address this limitation, we synthesized Co-doped MnO₂ nanoparticles with enhanced oxidase-mimicking activity through a facile chemical method. These Co-MnO₂ nanoparticles are characterized by the structural incorporation of Co ions into the MnO₂​ lattice, likely substituting Mn sites, which crucially induces a high density of surface oxygen vacancies (OVs), a key factor for enhanced catalysis. The presence of these OVs, confirmed by XPS, alongside the introduction of Co, leads to modulated e

SUBMITTER: Pham TH 

PROVIDER: S-EPMC12451438 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature