<i>Melissospora conviva</i> gen. nov., sp. nov., a novel actinobacterial genus isolated from beehive through cross-feeding interactions.

ABSTRACT: Most micro-organisms remain unculturable under standard laboratory conditions, limiting our understanding of microbial diversity and ecological interactions. One major cause of this uncultivability is the loss of access to essential cross-fed metabolites when bacteria are removed from their natural communities. During a bioprospecting campaign targeting actinomycetes of an Apis mellifera beehive, we identified five isolates (DT32, DT45^T, DT55, DT59 and DT194) that required co-cultivation for growth recovery, suggesting a dependence on microbial interactions in their native habitat. Whole-genome sequencing and phylogenetic analysis positioned these isolates within a distinct lineage of Micromonosporaceae, separate from the five officially recognized clades of the

SUBMITTER: Tellatin D 

PROVIDER: S-EPMC12451618 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature