Sight-Threatening Diabetic Retinopathy During and After Pregnancy-A Nationwide Matched-Cohort Study.

ABSTRACT:

Objective

To evaluate the risk of treatment of sight-threatening diabetic retinopathy (DR) defined as panretinal photocoagulation for proliferative DR or anti-vascular endothelial growth factor injections for diabetic macular edema (DME) during and after pregnancy compared with nonpregnant control participants.

Research design and methods

This was a matched cohort study of women with type 1 diabetes who gave birth in 2013-2022 and who had DR levels recorded in the national Danish Registry of Diabetic Retinopathy during and after pregnancy. Control participants consisted of nonpregnant women with type 1 diabetes, individually matched by baseline DR level. Data were collected from relevant national registers from 36 months before pregnancy until 36 months after.

Results

SUBMITTER: Larsson JE 

PROVIDER: S-EPMC12451835 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature