Combined Novel Microfocused Ultrasound and Microneedle Fractional Radiofrequency System for Multilayered Facial Rejuvenation: A Prospective, Randomized, and Split-Face Study.

ABSTRACT:

Background

With the aging population, the demand for skin anti-aging treatments has been steadily rising, prompting the development of advanced non-invasive therapies.

Aims

To evaluate the efficacy and safety of microfocused ultrasound (MFU) combined with microneedle fractional radiofrequency (MFR) for facial rejuvenation.

Methods

This study involved 26 patients experiencing facial laxity. Each patient received one full-face MFU treatment and one MFR treatment on one side of the face, which was randomly assigned. All treatments were performed on the same day. Facial photoaging parameters were assessed using VISIA, skin fat thickness changes were measured via ultrasound, and subjective evaluations were recorded at Months 0, 1, and 3. Side effects were recorded during t

SUBMITTER: Wang R 

PROVIDER: S-EPMC12452053 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature