Incompleteness of the circle of Willis affects sleep quality, cognitive function and inflammation in patients with primary hypertension.

ABSTRACT: To investigate whether incomplete Circle of Willis (Incomplete CoW) affects neuropsychological outcomes in patients with primary hypertension, a cross-sectional study was conducted involving 150 patients diagnosed with primary hypertension, a population at increased risk for neurovascular compromise. Magnetic Resonance Angiography was used to classify patients into two groups: Complete CoW (n = 41) and Incomplete CoW (n = 85). Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), and cognitive function was evaluated using the Mini-Mental State Examination (MMSE). PSQI scores were significantly higher in the Incomplete CoW group compared to the Complete CoW group, indicating poorer sleep quality in patients with an Incomplete CoW. A significant negative correlation was

SUBMITTER: Feng Y 

PROVIDER: S-EPMC12452657 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature