Compounds from medicinal plants produced in hairy root and transgenic hairy root cultures: a review.

ABSTRACT:

Background

Plants produce a wide variety of molecules, and some of them are of medicinal importance. Biotechnological systems such as suspended cells and hairy roots (HR) are used to produce plant compounds in a stable and controlled manner. HRs are obtained through a genetic transformation mediated by Rhizobium rhizogenes (R. rhizogenes), a Gram-negative bacterium that randomly inserts the transfer DNA (T-DNA) from the root-inducing plasmid (pRI) into the chromosome of a plant cell. Gene expression of T-DNA in plant cells induces a metabolic change to promote HR syndrome. The primary benefits of producing medicinal plant compounds in these biotechnology systems include the large yield of organ-specific bioactive compounds, production of de novo secondary metab

SUBMITTER: Urquiza-Lopez A 

PROVIDER: S-EPMC12452944 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature