Polysubstance use patterns among individuals applying for opioid use disorder treatment in the U.S.

ABSTRACT:

Objective

The prevalence of polysubstance use is known to be high among individuals who use/misuse drugs. This study aims to extend existing research by (a) measuring polysubstance use through objective drug testing rather than fallible self-reports, (b) determining the most frequent three- and four-substance combinations instead of being limited to typical two-substance combinations, and (c) examining a comprehensive panel of substances beyond those commonly studied.

Method

Participants were a convenience sample of individuals applying for methadone maintenance treatment in 11 clinics across 7 states (n= 1098, 43.2% female). Participants voluntarily provided oral fluid and urine specimens to the study during clinic intake that were tested for 22 types of substances by liqui

SUBMITTER: Lee-Easton M 

PROVIDER: S-EPMC12453169 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature