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Risk factors for abdominal aortic aneurysm in general populations: A systematic review and meta-analysis.


ABSTRACT:

Background

Abdominal aortic aneurysm (AAA) has a high mortality rate after rupture. This study systematically explored the risk factors associated with AAA in the general population using a meta-analytic approach.

Materials and methods

We conducted a systematic search of PubMed, Embase, and Cochrane Library databases to identify relevant literature. The search was conducted through May 2025. Factors considered in more than three studies were included in the analysis. Odds ratios (ORs) with 95% confidence intervals (CIs) were used as effect estimates and all pooled analyses were performed using a random-effects model.

Results

Thirty-four studies reporting 34,551 AAA cases were selected for meta-analysis. Increased risk of AAA was associated with male (OR: 3.78; 95% CI:

SUBMITTER: Zhang P 

PROVIDER: S-EPMC12453230 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature