Jointly representing long-range genetic similarity and spatially heterogeneous isolation-by-distance.

ABSTRACT: Isolation-by-distance patterns in genetic variation are a widespread feature of the geographic structure of genetic variation in many species, and many methods have been developed to illuminate such patterns in genetic data. However, long-range genetic similarities also exist, often as a result of rare or episodic long-range gene flow. Jointly characterizing patterns of isolation-by-distance and long-range genetic similarity in genetic data is an open data analysis challenge that, if resolved, could help produce more complete representations of the geographic structure of genetic data in any given species. Here, we present a computationally tractable method that identifies long-range genetic similarities in a background of spatially heterogeneous isolation-by-distance variation. The method

SUBMITTER: Shastry V 

PROVIDER: S-EPMC12453258 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature