Posttransplant Health-economic Impact of Normothermic Machine Perfusion (Back-to-base Model): Advancing Donation After Circulatory Death Liver Transplants With Improved Outcomes and Reduced Wait Times.

ABSTRACT:

Background

The widespread use of normothermic machine perfusion (NMP) has enabled greater utilization of donation after circulatory death (DCD) liver grafts for transplantation. Use of NMP can cost an additional $40 000-$100 000 The aim of our study was to see whether the use of NMP would lower postoperative costs after DCD liver transplantation (LT).

Methods

Retrospective data of all DCD LTs performed at our center between August 19, 2022, and May 31, 2024, were analyzed. The OrganOx metra device, back-to-base, was used for NMP at our center. United Network for Organ Sharing data were used to present national DCD LT volumes and waitlist outcomes.

Results

Sixty-seven NMP and 44 static cold storage transplants were performed. In the NMP group, donors were older (50 ver

SUBMITTER: Punjala SR 

PROVIDER: S-EPMC12453322 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature