The First Whole Genome Sequencing of Historical Lichen Specimens Enables Genome-Wide Analysis of Fungal and Algal Symbionts.

ABSTRACT: With the advent of high-throughput sequencing techniques, natural history museums and herbaria have become new frontiers for genetic research. Genomic information from historical specimens has provided evidence to solve significant questions in broad research areas. However, access to such valuable genetic resources remains limited in lichens due to experimental challenges in extracting and amplifying highly degraded DNA in historical specimens. So far, only a handful of studies have reported successful sequencing of several short genetic markers from historical lichen specimens despite the increasing importance of genetic information in lichenology. Here, we aimed to establish an efficient method for sequencing the whole genome of historical lichen specimens. We modified a method used in

SUBMITTER: Kono M 

PROVIDER: S-EPMC12453609 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature