Comparative effectiveness of en-bloc vs. conventional transurethral resection for non-muscle-invasive bladder cancer A systematic review and meta-analysis.

ABSTRACT:

Introduction

Transurethral en-bloc resection of bladder tumor (ERBT) has emerged as an alternate technique to conventional transurethral resection of bladder tumor (cTURBT). While theoretically advantageous, the comparative effectiveness of ERBT across various technical approaches remains unclear. We performed an updated systematic review and meta-analysis to evaluate perioperative, pathologic, and oncologic outcomes of ERBT vs. cTURBT.

Methods

We systematically searched PubMed, EMBASE, Scopus, and Google Scholar for randomized controlled trials (RCTs) comparing ERBT and cTURBT. The primary outcome was recurrence-free survival (RFS). Secondary outcomes were operative time, complication rates, detrusor muscle presence, and need for repeated resection. Meta-analyses were perfo

SUBMITTER: Hinojosa-Gonzalez DE 

PROVIDER: S-EPMC12453885 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature