Association Between Platelet to High-Density Lipoprotein Cholesterol Ratio and Cardiometabolic Multimorbidity in Middle-Aged and Elderly Chinese Hypertensive Patients.

ABSTRACT: Hypertensive patients exhibit elevated risk for cardiometabolic multimorbidity (CMM). The platelet-to-high-density lipoprotein cholesterol ratio (PHR) has emerged as a biomarker for cardiovascular risk assessment. However, the precise relationship between PHR and CMM remains inconclusive. To assess the association between PHR and CMM risk among middle-aged and elderly Chinese hypertensive patients. We included patients with documented hypertension history using data from the China Health and Retirement Longitudinal Study. Participants were stratified into tertiles per baseline PHR. Logistic regression models examined the PHR-CMM risk association. To evaluate nonlinear relationships, restricted cubic splines (RCS) were built. Subgroup analyses were used to assess effect modification across

SUBMITTER: Zheng Y 

PROVIDER: S-EPMC12453961 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature