Identification of High-Risk Population for Mortality and Severe Clinical Outcomes Among Patients With Myasthenia Gravis: A Nationwide Population-Based Cohort Study in Korea.

ABSTRACT:

Background

Myasthenia gravis (MG) is a rare chronic neurological condition characterized by skeletal muscle weakness and fatigue. Some patients with MG have poorly controlled symptoms with conventional treatments. While new treatments could be considered in patients with poorly controlled MG, their costs are considerably higher and may impose a financial burden on patients and the national health insurance system. Therefore, we sought to identify high-risk populations for mortality and severe clinical outcomes among MG patients to effectively allocate health resources.

Methods

A population-based cohort study was conducted using the Health Insurance Review and Assessment database from South Korea (2007-2023). Among patients with incident MG, we defined six clinical criteria e

SUBMITTER: Woo J 

PROVIDER: S-EPMC12453975 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature