Isolated congenital diaphragmatic hernia and three-year neurodevelopmental outcomes.

ABSTRACT:

Background

To retrospectively investigate the developmental outcomes at 3 years of age in patients with congenital diaphragmatic hernia (CDH) using a multicenter collaborative research approach.

Methods

We evaluated patients with CDH and no other malformations born between 2010 and 2016 in seven facilities in the Japanese CDH Research Group. The developmental quotient (DQ) at 3 years of age was evaluated using the Kyoto Scale of Psychological Development 2001, the most standardized scale in Japan. Factors associated with a DQ score < 85 were also analyzed.

Results

Of 196 patients, developmental assessments at 3 years of age were performed in 132 patients (67%). Among these, 99 patients (75%) had a DQ score ≥ 85, 25 (19%) had a DQ score between 70 and 84, and 8 (6%) ha

SUBMITTER: Toyoshima K 

PROVIDER: S-EPMC12454112 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature