Body composition in prepubertal children with idiopathic premature adrenarche: implications for cardiometabolic health.

ABSTRACT:

Background

Premature adrenarche (PA) has been reported as a potential precursor of metabolic disease. We aimed to explore the interaction between body composition and cardiometabolic health of prepubertal children with PA.

Methods

This observational study comprised of 87 children with PA (15 boys, 8.0 ± 1.2 years) and 87 healthy sex- and age-matched controls. Body composition was measured by bioelectrical impedance analysis.

Results

Children with PA had a higher median BMI z-scores (P = 0.001), higher median fat percentage (P = 0.006), and lower muscle-to-fat z-scores (P = 0.050) compared to controls. There were no significant group differences in blood pressure percentiles and lipid profiles. Fat percentage of children with PA was positively correlated and the MFR z-

SUBMITTER: Ben Simon A 

PROVIDER: S-EPMC12454123 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature