Association of spicy food consumption with colorectal polyp and adenoma prevalence: findings from the Lanxi Pre-Colorectal Cancer Cohort (LP3C).

ABSTRACT:

Objective

This study examined the relationship between habitual spicy food intake and the risk of colorectal polyps and adenomas in a high-risk Chinese cohort.

Methods

We analyzed baseline data from 14,907 participants aged 40-80 years enrolled in the Lanxi Precolorectal Cancer Cohort (LP3C) between March 2018 and December 2022. Dietary intake was assessed using a validated, single-administered baseline food frequency questionnaire (FFQ), with food intake frequency categorized into quartiles for analysis. Endoscopically confirmed colorectal lesions were histologically characterized. Multivariable-adjusted logistic regression models (adjusted for age, sex, body mass index (BMI), smoking, etc.) quantified lesion risks across spicy food consumption quartiles, with restricted cu

SUBMITTER: Hu P 

PROVIDER: S-EPMC12454312 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature