Development and validation of a nomogram for early prediction of sepsis-induced coagulopathy: a multicenter study.

ABSTRACT:

Background

Sepsis-induced coagulopathy (SIC) is a vascular endothelial cell injury and coagulation disorder caused by sepsis. The aim of this study was to construct a nomogram model of the risk of early onset of SIC in patients with sepsis by analyzing the risk factors for in-hospital development of SIC.

Methods

Patients with sepsis admitted to the intensive care unit (ICU) of Hebei General Hospital and Handan Central Hospital (East District) from March 1, 2021 to March 1, 2024 were retrospectively included. Sepsis patients were divided into SIC and non-SIC groups according to whether SIC occurred during hospitalization. The patient data were randomly divided into training set and testing set in the ratio of 7:3. The data of sepsis patients admitted to the ICU of Hebei Gener

SUBMITTER: Tan R 

PROVIDER: S-EPMC12454385 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature