Clinically Silent Microinfarct Incidence and Risk Factors After Treatment of Unruptured Intracranial Aneurysms with Hydrophilic Polymer-Coated Flow Diverters.

ABSTRACT:

Purpose

Although flow diverters (FDs) revolutionized the treatment of unruptured intracranial aneurysms (UIAs), clinically silent microinfarcts (SMs) are consistently detected in postprocedural diffusion-weighted imaging (DWI), and their clinical consequences remain unknown. This study examined the incidence of, and factors associated with, SM development after the use of two surface-modified FDs: the p48MW-HPC and p64MW-HPC.

Methods

A non-concurrent cohort study was conducted in 404 consecutive patients with UIAs treated with these two FDs between January 2020 and July 2023. The primary endpoint was the number of asymptomatic DWI lesions within 72 h after the procedure.

Results

SMs were detected in 58.2% of the cases, and ≥ 20 lesions were identified in 7.2% of cases

SUBMITTER: Khanafer A 

PROVIDER: S-EPMC12454470 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature