Neoadjuvant Treatment and Postoperative Complications After Surgery for Esophageal Cancer: A Population-Based, Nationwide Study in Finland.

ABSTRACT:

Background

The role of neoadjuvant treatment and its modalities in the risk of complications after esophagectomy in national practice is unclear. The aim of this study was to compare postoperative complications after neoadjuvant treatment (nT) and upfront surgery (US), neoadjuvant chemoradiotherapy (nCRT) and neoadjuvant chemotherapy (nCT), and to assess the effect of complications from neoadjuvant treatment in surgical risk.

Patients and methods

All patients undergoing esophagectomy for esophageal cancer in Finland in 2005-2016 were included. Incidences of all postoperative complications defined by the Esophagectomy Complications Consensus Group as well as major complications, 90-day mortality, and hospital and ICU stay were reported stratified by treatment strategy (nT ver

SUBMITTER: Sirvio VEJ 

PROVIDER: S-EPMC12454505 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature