Outcomes and Predictors of Flow Improvement After Transcatheter Aortic Valve Replacement in Patients With Low-Flow Low-Gradient Aortic Stenosis.

ABSTRACT:

Background

Flow is known to typically improve after transcatheter aortic valve replacement (TAVR); however, the characteristics correlating with improvement are still unclear. This study sought to explore the outcomes of patients with low-flow low-gradient aortic stenosis (LFLG AS) and flow improvement following TAVR compared to those without flow improvement, in addition to the predictors of flow improvement.

Methods

This is a retrospective cohort of patients >18 years of age who underwent TAVR at Cleveland Clinic between 2016 and 2020. Only patients with aortic valve area <1 cm², aortic valve mean gradient <40 mmHg, and stroke volume index (SVI) ​<35 mL/m² were included. Patients were classified into 2 groups according to whether SVI improved by 20% o

SUBMITTER: Besir B 

PROVIDER: S-EPMC12455137 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature