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Association of frailty with perioperative outcomes after mastectomy with and without immediate breast reconstruction.


ABSTRACT:

Background

Frailty has been recognized as an independent risk factor for adverse postoperative outcomes. Coding based frailty instruments such as the Modified Frailty Index (mFI-5) are increasingly incorporated into risk models to provide better prediction of mortality, and complications. However, few have examined the large-scale utility of mFI-5 in the context of mastectomy and breast reconstruction.

Methods

All elective adult (≥ 18 years) hospitalizations in women for mastectomy, with and without immediate breast reconstruction (IBR) were identified in the 2016-2022 National Inpatient Sample. Patients with an mFI-5 score ≥ 2 were considered Frail. Multivariable regression models were constructed to evaluate the association of frailty with major complications, length of st

SUBMITTER: Bilgili G 

PROVIDER: S-EPMC12455203 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature