Liver resection versus radiofrequency ablation for hepatocellular carcinoma: A systemic review and meta-analysis.

ABSTRACT:

Background

Liver resection and radiofrequency ablation (RFA) are two common treatments for hepatocellular carcinoma (HCC). However, their efficacy and safety remain unclear. We aimed to conduct a systematic review and meta-analysis to compare the effectiveness and safety of these two treatments.

Methods

We searched multiple databases to identify randomized controlled trials (RCTs) that compared liver resection with RFA for the treatment of HCC. The primary outcome was 5-year overall survival rate. The secondary endpoint was the incidence of complications. We used RevMan 5.4 software to calculate the pooled effects and 95% confidence interval (CI).

Results

Ten RCTs and 35 cohort studies were included in this meta-analysis. The pooled OR for 5-year overall survival rate

SUBMITTER: He Z 

PROVIDER: S-EPMC12455236 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature