Adaptive vs Monthly Support for Weight-Loss Maintenance: A Randomized Clinical Trial.

ABSTRACT:

Importance

Weight regain is common after the end of initial weight-loss treatment. Existing extended care programs (which typically provide sessions once per month) improve long-term weight-loss outcomes, but with only modest effect vs control.

Objective

To determine whether weight regain is reduced via provision of telephone-based extended care on an adaptive (triggered by a study algorithm that estimates when individuals are at high risk for weight regain) vs static (provided once per month) schedule.

Design, setting, and participants

A randomized clinical trial conducted between October 2019 and November 2024 in areas within driving distance of Gainesville, Florida. Adults with obesity enrolled in a 16-week weight-loss program; those who lost 5% or more of their ba

SUBMITTER: Ross KM 

PROVIDER: S-EPMC12455375 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature