Seizure freedom after surgical resection of diffusion-weighted magnetic resonance imaging abnormalities.

ABSTRACT:

Objective

Successful epilepsy surgery requires accurate localization and removal of the epileptogenic zone. Neuroimaging helps detect structural brain abnormalities to guide surgery, but current clinical practice does not use diffusion-weighted magnetic resonance imaging (dwMRI). However, previous work has shown that diffusion abnormalities are present in epilepsy and may relate to the epileptogenic zone. Here, we investigate whether surgical resection of diffusion abnormalities relates to postoperative seizure freedom.

Methods

We investigated the association between surgical resection of diffusion abnormalities and postoperative seizure freedom in 200 individuals with drug-resistant focal epilepsy using dwMRI. A cohort of 97 healthy controls provided a normative baseline fo

SUBMITTER: Horsley J 

PROVIDER: S-EPMC12455403 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature