Cerebrospinal fluid and serum biomarkers in idiopathic intracranial hypertension: A systematic review.

ABSTRACT:

Objective

This study aimed to systematically review the literature on soluble biomarkers in adults with idiopathic intracranial hypertension (IIH).

Background

Idiopathic intracranial hypertension is a multifactorial disorder marked by elevated intracranial pressure without a clear cause. Although it primarily affects overweight women of reproductive age, its pathogenesis remains incompletely understood. Symptoms include headache and visual disturbances due to papilledema. Increasing attention has focused on soluble biomarkers in serum and to understand disease mechanisms and aid diagnosis and management.

Methods

This systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and registered in PROSPE

SUBMITTER: Romozzi M 

PROVIDER: S-EPMC12455426 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature