Size-Selective Functionalization of Sugars and Polyols Using Zeolites for Renewable Surfactant Production.

ABSTRACT: Diol functionalization with acetals in carbohydrates and polyols is ubiquitously used in protection chemistry and in the manufacture of several platform chemicals. However, the selective functionalization of molecules where multiple acetalization reactions can occur typically involves multiple protection/deprotection steps. Here, we show that zeolites can be used to size-selectively acetalize sugars and polyols in a single step, and we demonstrate the potential of this approach for producing functional chemicals and materials. We show that high selectivity is dependent on effective pore confinement, which is achieved by a careful pairing of the substrate size and the zeolite morphology. This zeolite-catalyzed strategy exhibited consistently good-to-excellent yields (70%-95%) of novel polyo

SUBMITTER: Sun S 

PROVIDER: S-EPMC12455472 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature