Antibiotic resistance and factors associated with colonization dynamics of <i>Staphylococcus aureus</i> and <i>Streptococcus pneumoniae</i> in healthy children in Lima, Peru.

ABSTRACT: Pneumococcal conjugate vaccines (PCVs) have influenced population dynamics of Streptococcus pneumoniae in the nasopharynx and may have contributed to increased Staphylococcus aureus colonization. This study assessed the prevalence of colonization, antibiotic resistance patterns, and associated risk factors for colonization and co-colonization of S. aureus and S. pneumoniae in healthy Peruvian children post-PCV introduction. Nasopharyngeal swabs from children <24 months were collected in five hospitals in Lima (2018-2019). Microbiological identification and antibiotic susceptibility tests were performed, and multinomial regression evaluated factors influencing colonization. Among 894 children, 19.7% were colonized with S. aureus, 20.3% with S. pneumonia

SUBMITTER: Li Valverde VM 

PROVIDER: S-EPMC12455507 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature