Representation of Older Adults and Women in Randomized Trials of Noninvasive Imaging for Chest Pain.

ABSTRACT:

Background

Noninvasive imaging is widely used for both initial diagnosis and guided management of ischemic heart disease. Older adults and women with ischemic heart disease may have different responses to imaging and subsequent treatment outcomes compared to younger adults and men. We aimed to study the representation of older adults and women in randomized controlled trials of noninvasive imaging among patients with acute and stable chest pain.

Methods

We conducted a systematic search across PubMed, ClinicalTrials.gov, and guidelines to identify randomized controlled trials of noninvasive imaging-guided diagnosis and management for ischemic heart disease that were published between 2002 and 2023. Participation-to-prevalence ratio (PPR) was estimated for age subgroups of <65

SUBMITTER: Lim P 

PROVIDER: S-EPMC12455676 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature