Detecting rs-fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability.

ABSTRACT:

Background

Preserved resting-state functional MRI (rs-fMRI) networks are typically observed in Disorders of Consciousness (DOC). Despite the widespread use of rs-fMRI in DOC, a systematic assessment of networks is needed to improve the interpretability of data in clinical practice. We investigated functional connectivity of the main networks, combining structural MRI to obtain a description of the most observed networks in DOC, their diagnostic ability, and whether they can be related to clinical assessment.

Methods

A group of 109 chronic patients [65 vegetative state/unresponsive wakefulness state (VS/UWS), 34 minimally conscious state (MCS), and 10 emerged from MCS (eMCS)], with different etiologies, and 34 control subjects underwent multimodal assessment. Rs-fMRI data wer

SUBMITTER: Medina Carrion JP 

PROVIDER: S-EPMC12455880 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature