Vitamin B₁₂ release through bacteriophage-mediated cell lysis of the marine bacterium <i>Sulfitobacter</i> sp. M39.

ABSTRACT: Vitamin B₁₂ (B₁₂) is an essential cofactor for vital metabolic processes in both prokaryotes and eukaryotes. De novo B₁₂ biosynthesis is exclusively carried out by a modicum of prokaryotes, although being required by most organisms. Recently, it has been demonstrated that not all B₁₂-prototrophic bacteria voluntarily share this vital cofactor and, therefore, are termed B₁₂-retainers. Consequently, low biosynthesis potential and limited voluntary release lead to a large discrepancy between availability and demand for B₁₂ in the ocean, indicating that release of B₁₂ may be an important control. Hence, in this study, we examined a specific release process, cell lysis after phage infection. We isolated bacterio

SUBMITTER: Sultana S 

PROVIDER: S-EPMC12456174 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature