Influence of age and sex on the relative biological effectiveness of 13-keV/μm carbon ions for lifespan shortening of B6C3F1 Mice.

ABSTRACT: Epidemiological studies of Japanese atomic bomb survivors indicate that the risk of cancer from radiation exposure is higher in individuals who are relatively young at the time of exposure, with women facing a more significant risk compared to men. However, this type of data is limited for other radiation types, such as particle radiations. Low linear energy transfer (LET) carbon ions are a type of particle radiation to which humans may be exposed as cosmic radiation during long-duration space missions and as radiation passing through healthy tissue during carbon ion radiotherapy. This raises concerns about the risk of late complications, including cancer development. To address these issues, we examined the lifespan of mice after exposure to γ rays or low-LET carbon-ion beams, assessed th

SUBMITTER: Kakinuma S 

PROVIDER: S-EPMC12456818 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature