Characteristics and six-month viral load suppression of clients presenting with advanced HIV disease in South Africa.

ABSTRACT: Despite advances in antiretroviral therapy (ART), a notable proportion of individuals still present with advanced HIV disease (AHD) at treatment initiation, defined by CD4 < 200 cells/µL or WHO stage 3/4. This group experiences higher mortality and more opportunistic infections. While guidelines exist, they often do not address AHD clients specific needs early in treatment. Addressing these gaps could improve outcomes. Between September 2022 and June 2023, we surveyed a sequential sample of clients initiating ART or ≤6 months post-initiation at 18 primary healthcare facilities across three provinces. This observational cohort collected socio-demographic data, HIV care history, and service delivery preferences, and linked surveys to routine medical records and described client characteristi

SUBMITTER: Kachingwe E 

PROVIDER: S-EPMC12456826 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature