The relationship between albumin-corrected anion gap and hyperuricemia and its role in cardiovascular risk assessment: mediation effect analysis of triglycerides and non-high-density lipoproteins.

ABSTRACT:

Background

This study examines the relationship between Albumin-Corrected Anion Gap (ACAG) and hyperuricemia (HUA), as well as its potential mechanisms linking HUA to cardiovascular diseases. While HUA is associated with cardiovascular conditions, whether it is an independent risk factor remains unclear. ACAG, an indicator of acid-base balance, has prognostic value in cardiovascular outcomes, but its relationship with HUA has not been explored.

Methods

Data from 4,588 adults who visited Guangdong Provincial Hospital of Chinese Medicine between January and December 2023 were analyzed. HUA was defined as a serum uric acid (SUA) level >420 μmol/L, with the remaining participants categorized as Non-HUA. SPSS, R, and "Zstats" software were used for data analysis.

Results

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SUBMITTER: Yan M 

PROVIDER: S-EPMC12457168 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature