Assessing dosimetric benefit from daily online adaptive radiation therapy for esophageal cancer.

ABSTRACT: A cohort of 19 esophageal cancer patients treated at our institution were analyzed to assess the clinical feasibility and dosimetric benefit from daily adaptive radiation therapy (ART). An Ethos-planning template was developed to generate the initial ethos reference plan and daily adaptive plans using 9-field IMRT for reduced on-treatment optimization time. The template included relevant OAR goals and used an institutionally validated esophagus RapidPlan model. Clinical planning margins were used. Ethos-generated plans were validated against the clinically-approved plans which used 2-arc VMAT. Weekly on-treatment CBCT images were used to simulate doses from daily nonadaptive and adaptive techniques using the Ethos 2.0 Emulator. Timing data was recorded for each fraction. Dose metrics from

SUBMITTER: Kubiatowicz A 

PROVIDER: S-EPMC12457208 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature