Adverse events during radical prostatectomy and their association with recurrence and death.

ABSTRACT:

Objectives

The objective was to explore if adverse events during radical prostatectomy for prostate cancer were associated with oncological outcomes. A further objective was to identify risk factors for adverse events.

Methods

A post-hoc study nested in a prospective, controlled trial of radical prostatectomy by robot assisted laparoscopic or open retropubic approach in Sweden. Adverse events during surgery were collected from clinical record forms (CRFs) filled out by the surgeon at operation. Recurrence was identified from CRFs and patient reports, cause of death through the Swedish National Cause of Death Register. Recurrence was defined as undetectable PSA 6-12 weeks after prostatectomy followed by PSA > 0.25 ng/ml or treatment for prostate cancer recurrence. Cox regress

SUBMITTER: Erestam S 

PROVIDER: S-EPMC12457513 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature