Evaluating negative-pressure wound therapy after abdominoperineal resection: a systematic review of efficacy and technical variability.

ABSTRACT:

Background

Perineal wound complications after abdominoperineal resection (APR) for anal or low rectal cancer remain a significant clinical concern, frequently leading to surgical site infections (SSIs), wound dehiscence, and delayed healing. These complications contribute to increased patient morbidity, prolonged hospitalization, and higher healthcare costs. Prophylactic negative pressure wound therapy (pNPWT) has been proposed to improve wound outcomes in this context, but evidence regarding its effectiveness remains inconclusive.

Objective

This systematic review evaluates the clinical outcomes and technical application of pNPWT in closed perineal wounds following APR, with a focus on its potential impact on SSIs, wound dehiscence, and healing time.

Methods

A systema

SUBMITTER: Litchinko A 

PROVIDER: S-EPMC12457546 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature