Associations between air pollution and relative leukocyte telomere length among northern Swedish adults based on findings from the Betula study.

ABSTRACT: Air pollution is increasingly discussed as a risk factor for dementia, but the biological mechanisms are not yet fully understood. Biological markers like telomere length are relevant to study with air pollution, as they are associated with aging and dementia. The study aimed to investigate the relationship between source-specific air pollution exposure and telomere length in a low-level air pollution area, and whether this potential relationship depended on future dementia status. The data originated from the Betula study in Northern Sweden, where 509 participants recruited between 1988 and 1995 were included to investigate the association between annual mean air pollution concentrations at the participants' residences and relative leukocyte telomere length using a linear regression model

SUBMITTER: Raza W 

PROVIDER: S-EPMC12457613 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature