Plasticity of interhemispheric motor cortex connectivity induced by brain state-dependent cortico-cortical paired-associative stimulation.

ABSTRACT: Transcallosal connectivity between the hand areas of the two primary motor cortices (M1) is important for coordination of unimanual and bimanual hand motor function. Effective connectivity of this M1-M1 pathway can be tested in the form of short-interval interhemispheric inhibition (SIHI) using dual-coil transcranial magnetic stimulation (TMS). Recently, we and others have demonstrated that the phase of the ongoing sensorimotor µ-rhythm has significant impact on corticospinal excitability as measured by motor evoked potential (MEP) amplitude, and repetitive TMS of the high-excitability state (trough of the µ-rhythm) but not other states resulted in long-term potentiation-like MEP increase. Here, we tested to what extent the phase of the ongoing µ-rhythm in the two M1 affects long-term chan

SUBMITTER: Ermolova M 

PROVIDER: S-EPMC12457623 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature