Complementary efficacy and molecular insights of <i>Polygonati rhizoma</i> polysaccharide for glycemic and lipid abnormalities in type 2 diabetes mellitus: a comprehensive review.

ABSTRACT:

Background

T2DM is a global health challenge characterized by insulin resistance and impaired glucose metabolism. Natural products, such as polysaccharides from medicinal plants, are increasingly explored for their potential in managing T2DM with fewer side effects compared to conventional drugs.

Aim

This review aims to comprehensively evaluate the effects of Polygonati Rhizoma Polysaccharide (PRP) on glucose and lipid metabolism in T2DM and elucidate its underlying molecular mechanisms.

Introduction

In recent years, numerous scientific studies have demonstrated that Polygonati Rhizoma Polysaccharide (PRP) exerts beneficial effects on type 2 diabetes mellitus (T2DM), enhancing both glucose and lipid metabolism. This article provides a comprehensive revie

SUBMITTER: Ma S 

PROVIDER: S-EPMC12457904 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature