On the Rheological Properties and Printability of Sodium Alginate-Carboxymethyl Chitosan Composite Solutions for Tissue Scaffold Printing.

ABSTRACT: Composites of sodium alginate (Alg) and carboxymethyl chitosan (CMCS) are used to 3D print tissue scaffolds, but the rheological properties and printability of these composites remain underreported, resulting in time-consuming trial-and-error printing. This study investigates these properties to rigorously design the 3D printing process. Dynamic shear tests characterize viscoelastic and frequency-dependent properties, while steady shear tests assess the apparent viscosity and temperature-dependent viscosity. A novel approach based on mass flow rate models guides the printing of two-layer scaffolds for printability analysis. Brightfield microscopy and printability indexes quantify the deviations between printed and designed scaffolds, defined as printability. Results show that Alg predomina

SUBMITTER: Tabil XL 

PROVIDER: S-EPMC12457989 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature