RibofootPrinter: A precision python toolbox for analysis of ribosome profiling data.

ABSTRACT: Ribosome profiling is a valuable methodology for measuring changes in a cell's translational program. The approach can report how efficiently mRNA coding sequences are translated and pinpoint positions along mRNAs where ribosomes slow down or arrest. It can also reveal when translation takes place outside coding regions, often with important regulatory consequences. While many useful software tools have emerged to facilitate analysis of these data, packages can become complex and challenging to adapt to specialized needs. We therefore introduce ribofootPrinter, a suite of Python tools designed to offer an accessible and modifiable set of code for analysis of data from ribosome profiling and related types of small RNA sequencing experiments. Alignments are made to a simplified transcriptome

SUBMITTER: Kerkhofs K 

PROVIDER: S-EPMC12458181 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature