Post-acute dyslipidemia and abnormal BMI in children and adolescents with COVID-19: An EHR Cohort Study from the RECOVER Initiative.

ABSTRACT:

Background

Adults with SARS-CoV-2 infection have shown higher risks of dyslipidaemia and abnormal body mass index (BMI). Whether similar associations exist in children and adolescents is unclear.

Method

We did a retrospective cohort study using the RECOVER paediatric Electronic Health Record (EHR) datasets from 25 US children's hospitals, covering March 2020 to September 2023. For dyslipidaemia analyses, we included 384,289 patients aged 0-21 years with at least 6 months of follow-up and 1,080,413 COVID-19-negative controls. For BMI analyses, we included 285,559 patients aged 2-21 years and 817,315 controls. Documented infection was defined as a positive PCR, serology, or antigen test, or a clinical diagnosis of COVID-19 or post-acute sequelae of SARS-CoV-2. Outcomes were ne

SUBMITTER: Lei Y 

PROVIDER: S-EPMC12458518 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature