Triglyceride-Glucose Index: a novel prognostic predictor for postoperative cerebral infarction in off-pump coronary artery bypass grafting - insights from a nationwide multicentre study.

ABSTRACT:

Background

Postoperative cerebral infarction following coronary artery bypass grafting (CABG) for multivessel coronary artery disease (CAD) is a major complication and is associated with insulin resistance (IR). This study used the Triglyceride-Glucose (TyG) Index, a robust indicator of IR, to assess its association with cerebral infarction and other adverse events in patients with off-pump CABG (OPCABG).

Methods

This retrospective observational study included 3654 CAD cases from eight centres across China. The primary outcome was postoperative cerebral infarction. The predictive role of the TyG Index was evaluated using multivariate logistic regression and restricted cubic spline regression. Receiver operating characteristics analysis was conducted to assess its impact on m

SUBMITTER: Wang S 

PROVIDER: S-EPMC12458668 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature