Association between fat-to-muscle ratio and secondary osteoporosis in rheumatoid arthritis: a cross-sectional study at a tertiary hospital in China.

ABSTRACT:

Objectives

To investigate the correlation between fat-to-muscle ratio (FMR) or other body composition and secondary osteoporosis (OP) in patients with rheumatoid arthritis (RA) and to develop a predictive model using FMR and related clinical factors.

Design

Cross-sectional observational study with machine learning-based risk modelling.

Setting

Tertiary hospital in eastern China, secondary care level.

Participants

A total of 670 hospitalised RA patients (135 males and 535 females; aged 58.00 (50.00-67.00) years; disease duration 8.00 (2.00-16.00) years) and 126 healthy controls were recruited between October 2019 and October 2022. There were no differences in basic indicators such as gender, age distribution and body mass index between the two groups. RA diagnos

SUBMITTER: Shi JT 

PROVIDER: S-EPMC12458750 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature