Relationship between anti-diabetic medication use and glycaemic control: a retrospective diabetes registry-based cohort study in Singapore.

ABSTRACT:

Objective

This study aimed to determine the association between diabetes mellitus (DM) medication use and glycaemic control.

Design

This was a retrospective diabetes registry-based cohort study.

Setting

Singapore.

Participants

Patients aged 18 and above with incident DM in the SingHealth Diabetes Registry from 2013 to 2020 were included. The entire study period included a 1 year baseline period, a 1 year observation period and a 3 month outcome period.

Outcome measures

Drug use was measured using the proportion of days covered (PDC), and the changes in glycated haemoglobin (HbA1c) between the outcome and baseline periods were assessed. The associations between baseline HbA1c and PDC ≥0.80 and between PDC and change in HbA1c were analysed using logistic r

SUBMITTER: Chan SL 

PROVIDER: S-EPMC12458772 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature