Chitosan nanocarriers loaded with Egyptian Calligonum comosum L'Her. Extract: an eco-friendly approach for investigating triple-action biological activities.

ABSTRACT:

Background

Calligonum comosum L'Hér. is a large perennial shrub that grows in the desert. This plant inhabits much of the Egyptian desert, but has not yet been scientifically validated. Herein, we demonstrate the antimicrobial, anti-inflammatory, antioxidant, and anticancer properties of the ethanolic extract of the Egyptian C. comosum (CE) and its novel eco-friendly chitosan nano-formula (CE/CsNPs), which is prepared using citrate as a crosslinker.

Methods

The produced plant ethanolic extract (CE) was chemically analyzed. The eco-friendly CE/CsNPs were successfully developed through the conjugation of CE with different concentrations (200, 350, and 400 mg/100 mL) within the chitosan nanoparticle; then, it was fully characterized for the determination of the optimum formula

SUBMITTER: Khedr YI 

PROVIDER: S-EPMC12459056 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature